STAMP: Predicting Out-of-Distribution Generalization without Target Data

Predicting whether a trained model will generalize under distribution shift remains difficult, especially when target-domain data are unavailable. We introduce STAMP (Semantic Temporal Augmented Model Prediction), a source-only, target-label-free criterion that estimates out-of-distribution (OOD) performance from paired source-domain images. STAMP computes the output-space correlation ratio η^2=S_B/S_T by contrasting semantically stable pairs with random pairs: higher η^2 indicates that model outputs vary with semantic identity rather than nuisance variation. On 44 chest X-ray models spanning CNNs, ViTs, MetaFormers, foundation models, and SSL/VLM probes, temporal STAMP attains Spearman correlations of 0.844--0.855 with macro AUROC on VinDr-CXR, CheXpert, and MIMIC-CXR; a class-matched variant improves single-class RSNA from 0.311 to 0.663. STAMP attains the best average source-only medical ranking and outperforms the target-domain ATC and AoTL estimators without any target data. On 27 ImageNet models, temperature-scaled STAMPTS attains ρ{=}0.984 on ObjectNet and ρgeq0.905 on four additional distribution shifts, with partial correlations of 0.662--0.949 after controlling for ImageNet accuracy. Requiring approximately 12s per model on one GPU, STAMP is a practical pre-deployment model-selection and auditing tool.